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Abstract
The management of neurological disorders heavily relies on neurotherapeutic drugs, but notable concerns exist regarding their possible negative effects on reproductive health. Traditional preclinical models often fail to accurately predict reprotoxicity, highlighting the need for more physiologically relevant systems. Organoid models represent a promising approach for concurrently studying neurotoxicity and reprotoxicity, providing insights into the complex interplay between neurotherapeutic drugs and reproductive systems. Herein, we have examined the molecular mechanisms underlying neurotherapeutic drug-induced reprotoxicity and discussed experimental findings from case studies. Additionally, we explore the utility of organoid models in elucidating the reproductive complications of neurodrug exposure. Have discussed the principles of organoid models, highlighting their ability to recapitulate neurodevelopmental processes and simulate drug-induced toxicity in a controlled environment. Challenges and future perspectives in the field have been addressed with a focus on advancing organoid technologies to improve reprotoxicity assessment and enhance drug safety screening. This review underscores the importance of organoid models in unraveling the complex relationship bet
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Canadian Beef Podcast
We have Quinton Eriya on to discuss the 2024 New York Pro, and talk plans for Toronto Pro and beyond!
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**Challenges of competition preparation (00:26:48)**
Exploration of the challenges and adjustments required in competition preparation based on judges' feedback.
**Advantages of competing at home (00:27:12)**
Exploring the advantages of competing in familiar surroundings and the impact on personal and family support.
Toronto Pro competition (00:32:38)
Cali Pro Top five predictions (00:41:31)
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FIT MODEL Unusual YEAR'S Concern W/ Fin BEASTWOOD & SKYLAR SCHUMM | River Beef Podcast #153
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